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Magnetic Resonance Imaging with Gadolinium Contrast Agent in Small Deep (Lacunar) Cerebral Infarcts
Arch Neurol 50:175-180, Regli,L.,et al, 1993
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Article Abstract
Non-contrast-enhanced MR imaging allowed precise clinicotopographic correlation in five(38%)of 13 patients with SDCI symptoms in the internal carotid artery territory.After Gd-DTPA administration,precise clinicotopographic correlation improved in 11(85%)of 13 patients.In five patients,precise correlation was possible only after Gd-DTPA enhancement. Nonenhanced MR imaging allowed precise clinicotopographic correlation in 15(83%)of 18 patients with SDCI symptoms in the vertebrobasilar territory. After Gd-DTPA administration,we could establish precise clinicotopographic correlation in all patients with SDCIs in the vertebrobasilar territory.In three patients,precise correlation was possible only after Gd-DTPA contrast enhancement.In seven(23%)of 31 patients,Gd-DTPA failed to enhance symptomatic lesion:in five patients MR scans were performed early(less than 7 days)and in two patients later in the course(greater than 7 days). Although Gd-DTPA administration is unlikely to improve the sensitivity of MR images in visualizing SDCIs,it significantly improves the rate of precise clinicoanatomic correlation.All enhancing lesions showed precise clinicotopographic correlation.Enhancement may be absent in the acute phase(less than 7 days).
 
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cerebrovascular accident
gadolinium
lacunar infarction
MRI
MRI,abnormal
MRI,contrast enhanced
MRI,false negative

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